(D65) Disseminated intravascular coagulation [defibrination syndrome]

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25 030 in individuals diagnosis disseminated intravascular coagulation [defibrination syndrome] confirmed
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8 736 deaths with diagnosis disseminated intravascular coagulation [defibrination syndrome]
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35% mortality rate associated with the disease disseminated intravascular coagulation [defibrination syndrome]

Diagnosis disseminated intravascular coagulation [defibrination syndrome] is diagnosed Men are 15.85% more likely than Women

14 499

Men receive the diagnosis disseminated intravascular coagulation [defibrination syndrome]

3 872 (26.7 %)

Died from this diagnosis.

100
95
90
85
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75
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65
60
55
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10 531

Women receive the diagnosis disseminated intravascular coagulation [defibrination syndrome]

4 864 (46.2 %)

Died from this diagnosis.

Risk Group for the Disease disseminated intravascular coagulation [defibrination syndrome] - Men aged 60-64 and Women aged 75-79

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In Men diagnosis is most often set at age 0-5, 25-89
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Less common in men the disease occurs at Age 0-1, 5-24, 90-95+Less common in women the disease occurs at Age 0-1, 5-9, 15-19, 50-54, 95+
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In Women diagnosis is most often set at age 0-5, 10-14, 20-49, 55-94

Disease Features disseminated intravascular coagulation [defibrination syndrome]

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Absence or low individual and public risk
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Disseminated intravascular coagulation [defibrination syndrome] - what does this mean

Disseminated intravascular coagulation (dic) is a condition in which blood clots form throughout the body, leading to a decrease in the amount of circulating blood and a decrease in the ability of the blood to clot. this can be caused by a variety of medical conditions, such as infection, trauma, cancer, or pregnancy complications, and can lead to organ failure and death if not treated.

What happens during the disease - disseminated intravascular coagulation [defibrination syndrome]

Disseminated intravascular coagulation (dic) is a complex pathophysiologic process that occurs when the body's coagulation system is activated in an uncontrolled manner, leading to excessive and widespread activation of clotting factors and depletion of clotting factors and platelets. this results in widespread clotting within the small vessels, leading to clotting of vital organs and tissue, which can cause organ damage and even death if not treated promptly.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Prothrombin Time (PT)
  • Activated Partial Thromboplastin Time (aPTT)
  • Platelet Count
  • Fibrinogen Level
  • D-dimer Test
  • Liver Function Tests
  • Imaging Studies (CT scan, MRI)
  • Vascular Ultrasound
  • Coagulation Factor Assays
Additions:
  • Blood Culture Test
  • Thromboelastography (TEG)

Treatment and Medical Assistance

Main goal of the treatment: To reduce the risk of life-threatening bleeding and to restore the normal balance of clotting factors in the blood.
  • Administering medications to control bleeding.
  • Administration of anticoagulants to reduce the risk of clotting.
  • Administering fresh frozen plasma to replace clotting factors.
  • Administering platelet transfusions to replace platelets.
  • Administering cryoprecipitate to replace clotting factors.
  • Administering immunosuppressants to reduce inflammation.
  • Administering antibiotics to treat any underlying infection.
  • Monitoring of blood clotting levels.
  • Providing supportive care, such as oxygen therapy and IV fluids.
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16 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Disseminated intravascular coagulation [defibrination syndrome] - Prevention

The best way to prevent disseminated intravascular coagulation (dic) is to identify and treat the underlying cause of the condition. this may include prompt treatment of infections, removal of any underlying cancerous tumors, and prompt management of any underlying trauma. it is also important to ensure proper nutrition and hydration to support the body's natural coagulation processes.